Endochondral bone formation and development in the axial and appendicular skeleton
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منابع مشابه
Melorheostosis in proximal phalanx and metacarpal bone: a short-mid-term follow up
Melorheostosis is a rare sclerosing hyperostosis that affects the appendicular skeleton more than the axial skeleton. This disorder also affects the cutaneous and soft tissues and leads to the formation of fibrosis and contracture. Due to the unique features of melorheostosis (dripping candle wax appearance), plain radiographs are often sufficient for diagnosis. Herein we report a case of melor...
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The axial and appendicular skeleton of vertebrates develops by endochondral ossification, in which skeletogenic tissue is initially cartilaginous and the differentiation of chondrocytes via the hypertrophic pathway precedes the differentiation of osteoblasts and the deposition of a definitive bone matrix. Results from both loss-of-function and misexpression studies have implicated the related h...
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Mammals are remarkably diverse in limb lengths and proportions, but the number and kind of developmental mechanisms that contribute to length differences between limb bones remain largely unknown. Intra- and interspecific differences in bone length could result from variations in the cellular processes of endochondral bone growth, creating differences in rates of chondrocyte proliferation or hy...
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تاریخ انتشار 2004